TY - JOUR AU - Herlina, Nina AU - Yinke Magdalena Sinaga, Bintang AU - Siagian, Parluhutan AU - Mutiara, Erna PY - 2022/10/07 Y2 - 2024/03/28 TI - Association Between Vitamin D Levels With Mdr-Tb Patients With Household Contacts And Healthy People As Comparison JF - Proceedings of Malikussaleh International Conference on Health and Disaster Medicine (MICOHEDMED) JA - Proceedings of Malikussaleh International Conference on Health and Disaster Medicine VL - 1 IS - 1 SE - Articles DO - 10.29103/micohedmed.v1i1.20 UR - https://proceedings.unimal.ac.id/micohedmed/article/view/20 SP - 65-75 AB - <h1>Abstract</h1><p><strong>Background</strong>: The high incidence of pulmonary tuberculosis (TB) progressing into multidrugresistant TB (MDR-TB) has become a serious concern and caused a high mortality rate. The incidence of MDR-TB was 3.3% of new cases and 20% of cases of recurrent treatment. Low levels of vitamin D is a predisposing factor of MDR-TB, and family members in contact with the patient also show risk of infection. Currently, there is no study that compares vitamin D levels between MDR-TB patients and their household contact.</p><p><strong>Method</strong>: This is a case control study, with the number of samples of each group (MDR-TB patients, household contact, healthy controls) 40 subjects, respectively. Each member of each group were checked for vitamin D levels using enzyme-linked immunosorbent assay (ELISA) technique.</p><p><strong>Result</strong>: Mean levels of vitamin D in MDR-TB patients are 32.21, contact families 31.7 and healthy controls 26.86. There is a significant relationship between vitamin D levels and MDR-TB incidence (p=0.006).</p><p><strong>Conclusion </strong>: There was no significant association between vitamin D deficiency level with MDRTB. Vitamin D insufficiency was a protective factor for MDR-TB than in healthy control.&nbsp;&nbsp;</p> ER -