Evaluation of the Sensitivity and Specificity of the Tuberculosis Sign and Symptom (TBSS) Score in Comparison with Chest Radiography and Rapid Molecular Test for Diagnosing Tuberculosis Among Brick Kiln Workers

Authors

  • Retno Ariza Soemarwoto Departement of Pulmonology and Respiratory Medicine, Faculty of Medicine, University of Lampung, Indonesia
  • Anse Diana Valentiene Messah Departement of Radiology, Menggala General Hospital, Lampung, Indonesia
  • Pad Dilangga Departement of Pulmonology and Respiratory Medicine, Abdul Moeloek General Hospital, Lampung, Indonesia
  • Isura Febrihartati Departement of Pulmonology and Respiratory Medicine, Faculty of Medicine, University of Lampung, Indonesia

DOI:

https://doi.org/10.29103/micohedmed.v2i.1199

Keywords:

Tuberculosis, Tuberculosis Sign And Symptom Score, Chest Radiography, Rapid Molecular Test

Abstract

Purpose: The aim of this study is to evaluate the sensitivity and specificity of the Tuberculosis Sign and Symptom Score in comparison to chest radiography and rapid molecular testing among brick kiln workers in Pringsewu Regency. Patients and methods: This study uses a cross-sectional design. This study used a total sampling method, with total samples are 92. The study was conducted from February to March 2024 in a brick kiln located in Saribumi Village, Gading Rejo District, Pringsewu Regency, Lampung Province. Results: The sample in this study consists of 92 subjects. The majority of the sample is female, accounting for 77.3%, while males make up 22.8%. The most common age range is 41-60 years, representing 48.9% of the total. In terms of job categories, most workers are employed in the molding section. The screening with TBSS score and chest radiography yielded a sensitivity of 0.25, specificity of 0.93, positive predictive value of 0.14, and negative predictive value of 0.96. The sensitivity and specificity between the RTM test and TB ss score cannot be assessed because the results of the RTM examination showed that all respondents were negative for TB. Conclusion: All sputum examinations using rapid molecular testing (RMT) showed negative results. Its preventing the assessment of sensitivity and specificity for this method. This discrepancy may be due to suboptimal sample quality.

References

1. Noviyani A, Nopsopon T, Id KP. Variation of tuberculosis prevalence across diagnostic approaches and geographical areas of Indonesia. 2021;9:1–12. Available from: http://dx.doi.org/10.1371/journal.pone.0258809

2. WHO. Global Tuberculosis Report. Vol. t/malaria/, January. 2023.

3. Alsayed SSR, Gunosewoyo H. Tuberculosis : Pathogenesis , Current Treatment Regimens and New Drug Targets. 2023;

4. Hidayat A, Murti B, Soedarsono S, Wahyuni CU. Simple tuberculosis screening tool using signs , symptoms , and risk factors to reduce the missed opportunity in the older population. BMC Pulm Med [Internet]. 2022;1–8. Available from: https://doi.org/10.1186/s12890-022-02001-2

5. Thomas BE, Charles N, Watson B, Chandrasekaran V, Senthil R, Dhanalakshmi A, et al. Prevalence of chest symptoms amongst brick kiln migrant workers and care seeking behaviour : a study from South India. 2014;37(4):590–6.

6. Shriraam V, Srihari R, Gayathri T, Murali L. Active case finding for Tuberculosis among migrant brick kiln workers in South India. Indian J Tuberc. 2019 Jan 1;

7. Gahlot N, Rana K, Singh K. Workplace environment assessment of brick kiln units. 2020;9(1):433–8.

8. Syam DM, Arianty R, Sulaeman DS, Subagyo I. Risk Factors for Tuberculosis in the Work Area Community Health Center Sabang, Dampelas District, Donggala Regency. 2021;9:530–4.

9. APHL. Guidelines for Submission of Sputum Specimens for Tuberculosis Testing. Assoc Public Heal Lab. 2018;(April):1–7.

Downloads

Published

2024-11-29

How to Cite

Soemarwoto, R. A., Messah, A. D. V., Dilangga, P., & Febrihartati, I. (2024). Evaluation of the Sensitivity and Specificity of the Tuberculosis Sign and Symptom (TBSS) Score in Comparison with Chest Radiography and Rapid Molecular Test for Diagnosing Tuberculosis Among Brick Kiln Workers. Proceedings of Malikussaleh International Conference on Health and Disaster Medicine (MICOHEDMED), 2, 18–22. https://doi.org/10.29103/micohedmed.v2i.1199